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first-pass metabolism

См. также в других словарях:

  • First pass effect — The first pass effect (also known as first pass metabolism or presystemic metabolism) is a phenomenon of drug metabolism whereby the concentration of a drug is greatly reduced before it reaches the systemic circulation.After a drug is swallowed,… …   Wikipedia

  • Metabolism — The whole range of biochemical processes that occur within us (or any living organism). Metabolism consists both of anabolism and catabolism (the buildup and breakdown of substances, respectively). The term is commonly used to refer specifically… …   Medical dictionary

  • Pass — Contents 1 Admission and permission 2 Acronyms 3 Transport 4 …   Wikipedia

  • metabolism — /meuh tab euh liz euhm/, n. 1. Biol., Physiol. the sum of the physical and chemical processes in an organism by which its material substance is produced, maintained, and destroyed, and by which energy is made available. Cf. anabolism, catabolism …   Universalium

  • Drug metabolism — is the biochemical modification of pharmaceutical substances by living organisms, usually through specialized enzymatic systems. This is a form of xenobiotic metabolism. Drug metabolism often converts lipophilic chemical compounds into more… …   Wikipedia

  • Morphine — This article is about the drug. For other meanings, see Morphine (disambiguation). Morphia redirects here. For other uses, see Morphia (disambiguation). Not to be confused with Morphinae, Morphea, or Morpholine. Morphine …   Wikipedia

  • Heroin — Not to be confused with heroine. For other uses, see Heroin (disambiguation). Heroin …   Wikipedia

  • Chlorpromazine — Systematic (IUPAC) name …   Wikipedia

  • Bioavailability — In pharmacology, bioavailability (BA) is a subcategory of absorption and is used to describe the fraction of an administered dose of unchanged drug that reaches the systemic circulation, one of the principal pharmacokinetic properties of drugs.… …   Wikipedia

  • Anabolic steroid — cite journal author=Grishkovskaya I, Avvakumov GV, Sklenar G, Dales D, Hammond GL, Muller YA title=Crystal structure of human sex hormone binding globulin: steroid transport by a laminin G like domain journal=EMBO J. volume=19 issue=4… …   Wikipedia

  • Michel Eichelbaum — (* 19. Mai 1941 in Leipzig) ist ein deutscher Internist und Klinischer Pharmakologe. Er ist besonders bekannt durch seine Arbeiten über den Einfluss von Genmutationen auf die Pharmakokinetik von Arzneistoffen …   Deutsch Wikipedia

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